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Il-Gyu Ko Selected Research

Polydeoxyribonucleotides

5/2021Polydeoxyribonucleotide Attenuates Airway Inflammation Through A2AR Signaling Pathway in PM10-Exposed Mice.
1/2021Adenosine A2A Receptor Agonist Polydeoxyribonucleotide Alleviates Interstitial Cystitis-Induced Voiding Dysfunction by Suppressing Inflammation and Apoptosis in Rats.
1/2021Adenosine A2A receptor agonist polydeoxyribonucleotide ameliorates short-term memory impairment by suppressing cerebral ischemia-induced inflammation via MAPK pathway.
11/2020Polydeoxyribonucleotide Ameliorates Inflammation and Apoptosis in Achilles Tendon-Injury Rats.
6/2020Polydeoxyribonucleotide ameliorates lipopolysaccharide-induced acute lung injury via modulation of the MAPK/NF-κB signaling pathway in rats.
5/2020Combination Therapy With Polydeoxyribonucleotide and Pirfenidone Alleviates Symptoms of Acute Respiratory Distress Syndrome in Human Lung Epithelial A549 Cells.
1/2020Polydeoxyribonucleotide Exerts Therapeutic Effect by Increasing VEGF and Inhibiting Inflammatory Cytokines in Ischemic Colitis Rats.
11/2019Effect of Polydeoxyribonucleotide on Lipopolysaccharide and Sevoflurane-Induced Postoperative Cognitive dysfunction in Human Neuronal SH-SY5Y Cells.
6/2018Combination therapy with polydeoxyribonucleotide and proton pump inhibitor enhances therapeutic effectiveness for gastric ulcer in rats.
8/2017Polydeoxyribonucleotide Ameliorates Lipopolysaccharide-Induced Lung Injury by Inhibiting Apoptotic Cell Death in Rats.

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Il-Gyu Ko Research Topics

Disease

8Inflammation (Inflammations)
05/2021 - 05/2013
6B-Cell Lymphoma (Lymphoma, B Cell)
02/2022 - 08/2015
5Ischemia
01/2021 - 02/2009
4Brain Ischemia (Cerebral Ischemia)
01/2021 - 08/2015
4Encephalitis (Encephalitis, Rasmussen)
11/2020 - 01/2013
3Overactive Urinary Bladder (Overactive Bladder)
01/2017 - 03/2012
3Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
02/2014 - 10/2011
2Lung Injury
06/2020 - 08/2017
2Multiple Sclerosis
05/2020 - 04/2014
2Traumatic Brain Injuries (Traumatic Brain Injury)
08/2019 - 06/2018
2Spinal Cord Injuries (Spinal Cord Injury)
06/2019 - 01/2017
2Sleep Deprivation
01/2019 - 10/2018
2Crush Injuries
12/2018 - 01/2018
2Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
03/2018 - 03/2012
2Neurogenic Urinary Bladder (Bladder, Neurogenic)
01/2017 - 05/2014
2Stroke (Strokes)
08/2015 - 05/2013
2Erectile Dysfunction
01/2011 - 02/2009
1Parkinson Disease (Parkinson's Disease)
11/2021
1Sarcopenia
05/2021
1Lung Diseases (Lung Disease)
02/2021
1Edema (Dropsy)
01/2021
1Interstitial Cystitis (Interstitial Cystitis, Chronic)
01/2021
1Acute Lung Injury
06/2020
1Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
05/2020
1Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
05/2020
1Demyelinating Diseases (Demyelinating Disease)
05/2020
1Weight Loss (Weight Reduction)
05/2020
1Ischemic Colitis
01/2020
1Postoperative Cognitive Complications
11/2019
1Hypertrophy
06/2019
1Memory Disorders (Memory Loss)
02/2019
1Pain (Aches)
12/2018
1Osteonecrosis (Kienbock's Disease)
07/2018
1Bone Diseases (Bone Disease)
07/2018
1Stomach Ulcer (Gastric Ulcer)
06/2018
1Peripheral Nervous System Diseases (PNS Diseases)
01/2018
1Low Back Pain (Lumbago)
01/2018
1Brain Diseases (Brain Disorder)
01/2017

Drug/Important Bio-Agent (IBA)

10PolydeoxyribonucleotidesIBA
05/2021 - 08/2017
8LipopolysaccharidesIBA
11/2020 - 01/2013
6CytokinesIBA
01/2021 - 08/2017
6Brain-Derived Neurotrophic Factor (BDNF)IBA
02/2019 - 10/2011
5bcl-2-Associated X Protein (bcl 2 Associated X Protein)IBA
02/2022 - 08/2015
5Therapeutic UsesIBA
01/2021 - 07/2008
5DexmedetomidineFDA Link
01/2019 - 05/2013
4DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
02/2022 - 08/2015
4Caspase 3 (Caspase-3)IBA
02/2022 - 08/2015
4Dopamine (Intropin)FDA LinkGeneric
08/2019 - 10/2011
4Tamsulosin (Flomax)FDA LinkGeneric
03/2018 - 03/2012
3Proteins (Proteins, Gene)FDA Link
05/2021 - 06/2019
3Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
10/2013 - 02/2009
2Protein Kinases (Protein Kinase)IBA
11/2021 - 05/2021
2Adenosine A2A Receptor (Adenosine A2A Receptors)IBA
01/2021 - 01/2021
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2021 - 03/2012
2Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA
11/2020 - 03/2013
2Neuroprotective AgentsIBA
05/2020 - 09/2016
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2020 - 01/2013
2Dopamine Receptors (Dopamine Receptor)IBA
08/2019 - 10/2018
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2017 - 04/2013
2urinastatin (MR 20)IBA
08/2015 - 05/2013
2Methylphenidate (Ritalin)FDA LinkGeneric
02/2014 - 10/2011
2Tadalafil (Cialis)FDA Link
01/2011 - 02/2009
1Peptides (Polypeptides)IBA
08/2021
1Matrix Metalloproteinases (MMPs)IBA
08/2021
1PPAR gammaIBA
05/2021
1Adenosine Monophosphate (AMP)IBA
05/2021
1Adenosine (Adenocard)FDA LinkGeneric
02/2021
1Particulate MatterIBA
02/2021
1Mitogen-Activated Protein KinasesIBA
01/2021
13,7-dimethyl-1-propargylxanthineIBA
01/2021
1NF-kappa B (NF-kB)IBA
11/2020
1Phosphotransferases (Kinase)IBA
11/2020
1Pharmaceutical PreparationsIBA
05/2020
1InterferonsIBA
05/2020
1pirfenidoneIBA
05/2020
1CollagenIBA
01/2020
1Sevoflurane (Ultane)FDA LinkGeneric
11/2019
1Insulin-Like Growth Factor I (IGF-1)IBA
06/2019
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
02/2019
1atipamezoleIBA
01/2019
1Analgesics (Analgesic Drugs)IBA
12/2018
1Serotonin (5 Hydroxytryptamine)IBA
10/2018
1Diphosphonates (Bisphosphonates)IBA
07/2018
1Proton Pump InhibitorsIBA
06/2018
1naftopidilIBA
03/2018
1Interleukin-6 (Interleukin 6)IBA
08/2017
1deoxyuridine triphosphateIBA
01/2017
1Peptide Hydrolases (Proteases)FDA Link
01/2017
1Adrenergic Antagonists (Antiadrenergic Agents)IBA
01/2017
1Cytochromes c (Cytochrome c)IBA
01/2017
1Caspase 9IBA
01/2017
1Hypnotics and Sedatives (Sedatives)IBA
09/2016
1Glucose (Dextrose)FDA LinkGeneric
09/2016

Therapy/Procedure

4Therapeutics
05/2020 - 05/2014
2Transplantation
06/2019 - 05/2014
2Surgical Instruments (Clip)
12/2018 - 01/2018
2Intraperitoneal Injections
08/2017 - 04/2010
1Electroacupuncture
12/2018
1Traditional Medicine (Folk Remedies)
01/2018
1Ligation
01/2017